*PING* CK, blood doping discussion
Last Post 02/07/2016 03:38 PM by Kenny Gonzales. 16 Replies.
Author Messages
Dale

Posts:1767

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01/26/2016 09:56 AM
After my wreck I went to the doc for the INR check and it was 3.3
Normally I'm just below 2.0 and have never been above 2.3

No aspirin, no Advil but had been taking Percocet which contains acetaminophen.
My doc was out and his sub just told me just lower the warfarin amount.

Previously I was told acetaminophen is the pain reliever I could take but now there's evidence it is a warfarin multiplier in some people.

Sort of looking like I'd better just tough it out if I get hurt since there not much I can take.

Didn't you have an episode where your IRN spiked or was that Evan?
Did you ever find the reason it went nuts?
6ix

Posts:485

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01/26/2016 12:30 PM
Dale-

My INR will sit between 2-3 for months at a time without any issues and then WHAM, it's off the charts or really low. Was at 4.1 yesterday morning with zero dietary changes or anything out of the ordinary. That's high enough to be at risk of a brain bleed should I crash while out riding, so I'm stuck on the trainer. As for a pain reliever, I've been using naproxen which I believe is a generic version of Aleve. Works fine for me. Think it's aspirin you're supposed to steer clear of when on coumadin/warfarin/rat poison.

How is that massive bruise healing up after 'cross nationals? Did you enjoy your time in Asheville? Where did you end up staying? Get a chance to hit up any of the great restaurants?
Dale

Posts:1767

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01/26/2016 12:45 PM
Ashville was a blast and I plan on going back with my wife to vacation at some point. Since I was there with a couple of team mates we stayed at a cheap motel. Ate at a couple of the places downtown-- some Mexican place that was great and a couple of the bakery/ coffee shops. One of my team mates works with a women developmental team and we spent one evening with a team members family. It was a great trip.

Aspirin messes up the platelets clotting ability for the life of the platelet, Advil also interferes with clotting as long as it's in the system but once it's out then the red cells function normally so it works for generally sedentary people short term but does increase risk for bleeding.

It think acetaminophen is an issue for some people, not everyone.

A couple articles
http://www.pubfacts.com/detail/10512064/Warfarin-acetaminophen-drug-interaction-revisited.
http://www.jamda.com/article/S1525-8610(07)00324-6/abstract

Bruising is gone. Still a nice size but shrinking hematoma on my side and back. That was the hardest I've gone down and not broken anything or ended up in the ER.
Gonzo Cyclist

Posts:568

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01/26/2016 04:48 PM
ah ha, when I saw that bruise, something in me said, "Wow, I have not see that kind of bruising since my coumadin days" scary stuff, soooo glad to off that medication
My sweet spot was 2.5, aspirin and advil will spike it for sure, a few drinks will also spike it also.

you can imagine when I was on 11 meds after the heart attack, blood thinners, blood pressure meds, heart drugs etc, scary as hell.......I could just touch something with an arm and leg, and turn all kinds of black and blue
Dale

Posts:1767

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01/26/2016 08:03 PM
Didn't you survive a widow-maker a bunch of years ago? Yeah, with that many drugs all designed to prevent your blood from turning to mush inside I bet you'd bruise at the slightest bump.

Before the purple started to fade my whole side from knee to armpit was Technicolor.
79pmooney

Posts:3178

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01/26/2016 08:18 PM
Aspirin and platelets. Used to stay off aspirin because I was a regular platelets donor. I don't do that any more (my elbows said after 200+ of those needles "enough"; actually a Red Cross nurse said I shouldn't anymore). So I am free to use that drug which my CP knees love. Still don't use a lot. A bottle probably goes three years. But if I take one or two when my knees are sore, wow! Yes going to bed with knees that won't be the focus of my thoughts is nice, but waking up to really happy knees is much bigger. The relief is permanent (until I abuse my knees again).

Ben
79pmooney

Posts:3178

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01/26/2016 08:24 PM
While I am here and have an audience, I'm going to put it out there that I am going to do my best to get through another year without a crash. If that means riding like an old man at times (on bikes better than I raced) so be it. Rubber down, shiny side up is good. I've eaten enough pavement for a lifetime.

Next January, ask me if I succeeded.

Ben
Cosmic Kid

Posts:4209

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01/27/2016 03:32 PM
Yeah, right before IMWI in 2014 my INR got up into the mid-5's, IIRC. Noticed my urine was very dark (looked like tea) and went to see my doc. He was gonna do MRI / X-rays when I said "maybe we should check my INR?" LOL...classic.

Guys in ST were saying there is now a fast-acting reversing agent for Pradaxa. Another guy said he just skips his Eliquis dosage the day before a race and he is OK to race. He just resumes the next day.

Dunno about either of the claims, but I am definitely gonna look into them. If I can switch to the next-gen thinners and start bike racing again, I'm on it!
Just say "NO!" to WCP!!!!
zootracer

Posts:833

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01/27/2016 08:44 PM
pain is temporary, quitting is forever
Dale

Posts:1767

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01/27/2016 09:23 PM
You on the rat killer or the new stuff? The cost of warfarin is about three bucks a month vs three hundred for the new stuff. I'm on a high deductible plan so I stick with the cheap dope plus I like that it;s got a proven history.
Cosmic Kid

Posts:4209

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01/27/2016 09:26 PM
Still on the rat poison....and yeah, the next-gen pills are stoopid expensive. That will factor into any decision, as well.
Just say "NO!" to WCP!!!!
6ix

Posts:485

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01/31/2016 03:11 PM
So....refresh my memory here. If my INR is supposed to be between 2-3, it's probably too dangerous to race, right? I keep forgetting that part when I have visions of grandeur, thinking that I want to race crits again.

Of course, the other reality check is that I suffered like a dog riding outdoors today. All those hours on the trainer don't exactly translate well into the real-world.
Dale

Posts:1767

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01/31/2016 06:46 PM
6ix, my doc wants me at 2.0 +/- .2 I think therapeutic level is 2.0 but my doc is OK with me being slightly below since he knows I ride and race. He doesn't want me racing crits or big road races due to the likelihood of high speed wrecks. He's not thrilled about me racing cx or riding mbt but since he's one of my riding buddies he just gives me a "ride safe" lecture and told the rest of the group what to do if I hit my head hard.


My brother who has LFF also is supposed to be at 2.5 due to his being a pilot but he doesn't ride.


The higher the INR the greater risk for a brain bleed but as you know we have to balance the risk or the bleed or a clot.


I freely admit I'm putting myself at risk by racing or riding for that matter but my risk of dying due to obesity sitting on the couch is zero.
Cosmic Kid

Posts:4209

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01/31/2016 08:58 PM
Yeah, it is all about (life) balance. I decided for my family's sake that I wouldn't race on the road anymore, but still do tri's (less risk of going down because of some other idiot's poor decision). But I still end up training on the road, and let's face it, that is probably my highest risk factor. But my wife also knows what it is like to live with me when I am not riding, so (her) quality of life for factors in!

Just say "NO!" to WCP!!!!
6ix

Posts:485

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02/05/2016 02:15 PM
Wow, Dale and CK really nailed it with these statements: "I freely admit I'm putting myself at risk by racing or riding for that matter but my risk of dying due to obesity sitting on the couch is zero" and "...wife also knows what it is like to live with me when I am not riding." Perfectly sums it all up for me.
longslowdistance

Posts:2881

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02/06/2016 01:20 AM
It's not just how long one's life is, it's how wide and deep.

Ben, maybe time to put a freewheel and good brakes on the fixie?
Gonzo Cyclist

Posts:568

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02/07/2016 03:38 PM
Dale Said:
"Didn't you survive a widow-maker a bunch of years ago? Yeah, with that many drugs all designed to prevent your blood from turning to mush inside I bet you'd bruise at the slightest bump."
Yup, 9 years ago this June 21st, pretty crazy stuff, you guys start talking about rat poison, etc....and I just shudder.
When I was still on that stuff, took a pretty good shot to the head on the MTB, had to get checked out, everything was OK, they were a little upset about what I was doing, but I told them, " I have to live too!" and they understood

I hear Pmooney, I am always due for at least one good crash a year, but the last three years have all been on an MTB, a bit more unpredictable, and I'm always pushing the limits, so, it's bound to happen I guess,  the goal for me would be, no more ER visits.....


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